LO1280
Sigma

LOPAC¹²⁸⁰

Synonym

Library of Pharmacologically Active Compounds

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Descriptions

General description

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).

Other Notes

For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.

Features and Benefits

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

• Apoptosis
• G Proteins & Cyclic Nucleotides
• Gene Regulation & Expression
• Ion Channels
• Lipid Signaling
• Multi-Drug Resistance
• Neurotransmission
• Phosphorylation

SDFile provided to construct a database containing:

• Structure
• Primary Name
• Secondary Name
• Pharmacological Activity
• Product Number
• Rack Position

Properties

shipped in

dry ice

storage temp.

−20°C

References

Reference

Diamandis, P., et. al., Chemical genetics reveals a complex functional ground state of neural stem cells Nature Chem. Biol. 3(5), 268-273, (2007)

Lazo, J.S., et. al., Building a Pharmacological Lexicon : Small Molecule Discovery in Academia Mol. Pharmacol. 72, 1-17, (2007)

Benjamin, E.R., et. al., State-dependent compound inhibition of Nav1.2 sodium channels using FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents J. Biomol. Screen. 11(1), 29-39, (2006)

Rickardson, L., et. al., Image-based screening for the identification of novel proteosome inhibitors J. Biomol. Screen. 12(2), 203-210, (2007)

Safety

WGK Germany

Flash Point(F)

189 °F

Flash Point(C)

87 °C