M0503
Sigma

Mitomycin C from Streptomyces caespitosus

powder

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Molecular Formula

C₁₅H₁₈N₄O₅

Molecular Weight

334.33

CAS Number

50-07-7

Beilstein Registry Number

7231816

MDL number

MFCD00078109

PubChem Substance ID

24896555

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Descriptions

Frequently Asked Questions

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Biochem/physiol Actions

Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.

Other Notes

Vial contains 2 mg mitomycin C and 48 mg NaCl.

Properties

form

powder

storage temp.

2-8°C

References

Reference

Tomasz, M., Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235, 1204, (1987)

Ueda, M., Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C. Nucleic Acids Res. 12, 6673, (1984)

Y. Hashimoto et al. Acc. Chem. Res. 17, 403, (1984)

Merck

Merck 13,6236

Safety

Hazard Codes

Risk Statements

22-40

Safety Statements

36/37

WGK Germany

8-10

Related Categories

... Core Bioreagents > Antibiotics

... Antibiotics A to Z > Antibiotics G-M

... Antibiotics by Application > Antineoplastic and Immunosuppressive Antibiotics

... Chemical Structure Class > Aziridines

... Antitumor Agents > DNA Modification / Repair

... DNA metabolism > DNA Synthesis Inhibitors

... Mechanism of Action > Interferes with DNA Synthesis

M0503 - Product Information Sheet (87kb)

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

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