M157
Sigma

MEN-10,376

≥95% (HPLC), solid

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Amino Acid Sequence

Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH₂

Molecular Formula

C₅₇H₆₈N₁₂O₁₀

Molecular Weight

1081.22

CAS Number

135306-85-3

MDL number

MFCD00144736

PubChem Substance ID

24896670

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Descriptions

Biochem/physiol Actions

Potent and selective NK-2 tachykinin receptor antagonist.

Properties

assay

≥95% (HPLC)

form

solid

color

white

storage temp.

−20°C

References

Reference

Maggi, et al., In vivo evidence for tachykininergic transmission using a new NK-2 receptor-selective antagonist. J. Pharmacol. Exp. Ther. 257, 1172, (1991) abstract

Bartho, et al., Tachykininergic transmission to the circular muscle of the guinea pig ileum: Evidence for the involvement of NK-2 receptors. Br. J. Pharmacol. 105, 805, (1992) abstract

Patacchini, et al., Effect of newly developed tachykinin agonist and antagonists on the guinea pig isolated gallbladder. J. Pharmacol. Exp. Ther. 261, 191, (1992) abstract

Safety

WGK Germany

Related Categories

... Tachykinins > Antagonist

... Neuropeptides > Tachykinins

MSDS

Certificate of Analysis

More Information