M3445
Sigma

Magnolol

≥95% (HPLC), from plant

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Synonym

5,5′-Diallyl-2,2′-biphenyldiol

Molecular Formula

C₁₈H₁₈O₂

Molecular Weight

266.33

CAS Number

528-43-8

MDL number

MFCD00016658

PubChem Substance ID

24896843

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Descriptions

Biochem/physiol Actions

Bioactive plant component with antifungal,¹ antibacterial² and antioxidant effects.³ Magnolol also demonstrates anti-inflammatory activity by interferring with NF-κB signaling.⁴

Properties

biological source

from plant

assay

≥95% (HPLC)

storage temp.

2-8°C

References

Cited Reference

1. Bang, K.H., et al., Antifungal activity of magnolol and honokiol. Arch. Pharm. Res. 23, 46-9, (2000)

2. Ho., K.Y., et al., Antimicrobial activity of honokiol and magnolol isolated from Magnolia officinalis. Phytother Res. 15, 139-41, (2001)

3. Lo, Y.C., et al., Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation. Biochem. Pharmacol. 47, 549-53, (1994)

4. Lee, J., et al., Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-κB activation signaling. Planta Med. 71, 338-43, (2005)

Merck

Merck 13,5721

Safety

Hazard Codes

Risk Statements

37/38-41-51/53

Safety Statements

26-39-61

RIDADR

UN 3077 9/PG 3

RTECS

DV5105500