Immunogen
synthetic peptide corresponding to C-terminal human matrix metalloproteinase-1 (interstitial collagenase).
Specificity
By immunoblotting against the reduced protein, the antibody reacts with bands at 53 kDa and 51 kDa (the pro-form), as well as active forms. Also reacts with non-reduced MMP-1. Since the hemopexin domain is cleaved off to form the smallest active form of MMP-1, the antibody does not recognize the 21 kDa form of MMP-1.
Physical form
Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide