M4414
Sigma

Myristoyl coenzyme A lithium salt

min. 80%

Synonym

n-Tetradecanoyl Coenzyme A lithium salt

Molecular Formula

C₃₅H₆₂N₇O₁₇P₃S · xLi⁺

Molecular Weight

977.89 (free acid basis)

CAS Number

187100-75-0

MDL number

MFCD01310861

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Descriptions

Substrates

Long chain fatty acid (C14) covalently linked to Coenzyme A. Substrate for de novo fatty acid synthesis. Fatty acylation has been shown to block G protein-associated calcium release by a direct allosteric modification of a component of the GTP-activated process.

Properties

storage temp.

−20°C

References

Reference

Dittrich, F., et al., Fatty acid elongation in yeast-biochemical characteristics of the enzyme system and isolation of elongation-defective mutants. Eur. J. Biochem. 252, 477-485, (1998) abstract

Knoll, L.J, et al., Functional significance of myristoyl moiety in N-myristoyl proteins. Meth. Enzymol. 250, 405, (1995) abstract

Rys-Sikora, K.E., Modification of GTP-activated calcium translocation by fatty acyl-CoA esters. Evidence for a GTP-induced prefusion event. J. Biol. Chem. 269, 31607, (1994) abstract

Safety

WGK Germany

10-21