M6567
Sigma

Monoclonal Anti-MRP3 antibody produced in mouse

250 μg/mL, clone M₃II-21, tissue culture supernatant

Synonym

Anti-Multidrug Resistance Associated Protein 3

MDL number

MFCD02263753

Expand/Collapse All

Descriptions

Immunogen

fusion protein of MRP3 (amino acids 830-949).

Specificity

Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2, or MRP5 gene products.

Physical form

Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

Properties

antibody form

tissue culture supernatant

clone

M₃II-21

mol wt

antigen mol wt 190-200 kDa

species reactivity

human

concentration

250 μg/mL

application(s)

immunoblotting: 1:20-1:50

immunocytochemistry: 1:20-1:50 using acetone- or formaldehyde-fixed cytospin preparations

immunohistochemistry (frozen sections): 1:20 using acetone-fixed sections

isotype

IgG1

Gene Information

human ... ABCC3(8714)

shipped in

dry ice

storage temp.

−20°C

References

Reference

Kool, M., et al., Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5 homologs of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res. 57, 3537-3547, (1997) abstract

Scheffer, G.L., Specific detection of multidrug resistance protein MRP, MRP2, MRP3, MRP5 and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res. 60, 5269-5277, (2000) abstract

Kool, M., et al., MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc. Natl. Acad. Sci. USA 96, 6914-6919, (1999) abstract

Safety

WGK Germany