M8255
Sigma

Myristoyl chloride

≥99%

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Synonym

Tetradecanoyl chloride

Molecular Formula

CH₃(CH₂)₁₂COCl

Molecular Weight

246.82

CAS Number

112-64-1

Beilstein Registry Number

636924

MDL number

MFCD00000741

PubChem Substance ID

24897233

EG/EC Number

203-994-6

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Descriptions

Biochem/physiol Actions

Fatty acid containing 14 carbons. Covalent attachment of myristate is a common occurrence on a wide variety of viral and cellular proteins and plays a role in promoting membrane binding.

Properties

assay

≥99%

refractive index

n20/D 1.449(lit.)

250 °C/100 mmHg(lit.)

−1 °C(lit.)

density

0.908 g/mL at 25 °C(lit.)

storage temp.

−20°C

References

Reference

Resh, et al., Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim. Biophys. Acta 1451, 1-16, (1999) abstract

Goldberg, et al., Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell 95, 237-248, (1998) abstract

Beilstein

Beil. 2,IV,1138

reference

Aldrich MSDS 1, 1332:B / Corp MSDS 1 (2), 2483:A / FT-IR 2 (1), 1232:B / FT-IR 1 (1), 731:B / FT-NMR 1 (1), 1197:A / IR-Spectra (3), 427:F / IR-Spectra (2), 379:E / NMR-Reference 2 (1), 618:B / RegBook 1 (1), 853:L / Structure Index 1, 131:D:10

Safety

Hazard Codes

Risk Statements

34-37

Safety Statements

26-36/37/39-45

RIDADR

UN 3265 8/PG 2

WGK Germany

Flash Point(F)

235 °F

Flash Point(C)