M9411
Sigma

Myristicin from parsley leaf oil

≥85% (HPLC), oil

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Synonym

4-Methoxy-6-(2-propenyl)-1,3-benzodioxole

Molecular Formula

C₁₁H₁₂O₃

Molecular Weight

192.21

CAS Number

607-91-0

MDL number

MFCD00133549

PubChem Substance ID

24897334

EG/EC Number

210-146-9

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Descriptions

Biochem/physiol Actions

Myristicin induces the expression of glutathione S-transferase and cytochrome P450 (Cyp1a-1) in liver cells. May enhance detoxification of carcinogenic substances.

Properties

assay

≥85% (HPLC)

form

oil

color

clear, light yellow

storage temp.

2-8°C

References

Reference

Lee, H.S., et al., In vitro and in vivo metabolism of myristicin in the rat. J. Chromatogr. B. Biomed. Sci. Appl. 705, 367-372, (1998) abstract

Zheng., G.Q., et al., Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Carcinogenesis 13, 1921-1923, (1992) abstract

Ahmad, H., et al., Preferential overexpression of a class MU glutathione S-transferase subunit in mouse liver by myristicin. Biochem. Biophys. Res. Commun. 236, 825-8, (1997) abstract

Jeong, H.G., and Yun, C.H., Induction of rat hepatic cytochrome P450 enzymes by myristicin. Biochem. Biophys. Res. Commun. 217, 966-71, (1995) abstract

Jeong, H.G., et al., Murine Cyp1a-1 induction in mouse hepatoma Hepa-1C1C7 cells by myristicin. Biochem. Biophys. Res. Commun. 233, 619-22, (1997) abstract

Safety

Risk Statements

52/53

Safety Statements

RIDADR

UN 3082 9/PG 3

WGK Germany

RTECS

CY2625000