N3018
Sigma

(±)-Nornicotine

≥99% (TLC), liquid

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Synonym

2-(3-Pyridyl)pyrrolidine

3-(2-Pyrrolidinyl)pyridine

Molecular Formula

C₉H₁₂N₂

Molecular Weight

148.20

CAS Number

5746-86-1

Beilstein Registry Number

81968

MDL number

MFCD00016913

PubChem Substance ID

24897615

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Descriptions

Biochem/physiol Actions

Nicotinic acetylcholine receptor agonist; active metabolite of nicotine; tobacco alkaloid.

Properties

assay

≥99% (TLC)

form

liquid

color

yellow

solubility

H₂O: 50 mg/mL

Gene Information

rat ... Chrna4(25590)

mouse ... Chrna1(11435), Chrna7(11441)

storage temp.

2-8°C

References

Reference

Teng, L., Nicotinic-receptor mediation of S(−)nornicotine-evoked ³H-overflow from rat striatal slices preloaded with ³H-dopamine. J. Pharmacol. Exp. Ther. 283, 778, (1997) abstract

Bardo, M.T., Nornicotine is self-administered intravenously by rats. Psychopharmacology 146, 290, (1999) abstract

Ghosheh, O., Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2′-¹⁴C]nicotine. Drug Metab. Dispos. 27, 1448, (1999) abstract

Beilstein

Beil. 23,V,6,62

Safety

Hazard Codes

Risk Statements

20/21/22-36/37/38

Safety Statements

26-36/37

WGK Germany

RTECS

QS6350000

3-10

Related Categories

... Cholinergics > Agonists

... Ligand-Gated Ion Channels > Nicotinic Acetylcholine Receptor Modulators

MSDS

Certificate of Analysis

Certificate of Origin

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