N3385
Sigma

N-Nitroso-N-ethylurea

ISOPAC^®

zoom

1 of 1

Synonym

ENU

N-Ethyl-N-nitrosourea

Molecular Formula

C₃H₇N₃O₂

Molecular Weight

117.11

CAS Number

759-73-9

MDL number

MFCD00053635

PubChem Substance ID

24897640

EG/EC Number

212-072-2

Expand/Collapse All

Descriptions

Biochem/physiol Actions

DNA alkylating agent that is carcinogenic in many animal species. Induces benign and malignant tumors of numerous types, including the nervous tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissues, skin, and kidney.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Packaging

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.

Properties

storage temp.

−20°C

References

Reference

Fenske, T.S., et al., Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Cancer Res. 66, 5029-5038, (2006)

Pllyzos, A., et al, Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo[a]pyrene, etoposide and okadaic acid. Mutat. Res. 598, 73-84, (2006)

Safety

Hazard Codes

Risk Statements

45-46-61-20/21/22

Safety Statements

53-22-36/37/39-45

RIDADR

UN 2811 6.1/PG 3

WGK Germany

RTECS

YT3150000

N-Nitroso-N-ethylurea

ISOPAC®

ISOPAC^®