N4014
Sigma

Nystatin

powder, γ-irradiated, cell culture tested

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Synonym

Fungicidin

Mycostatin

CAS Number

1400-61-9

MDL number

MFCD00036240

PubChem Substance ID

24897362

EG/EC Number

215-749-0

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Descriptions

Biochem/physiol Actions

Mode of Action: Increases the permeability of the cell membrane of sensitive fungi by binding to sterols.
Antimicrobial spectrum: Yeasts and molds.

Preparation Note

Prepared from Nystatin (N 6261).

Reconstitution

Nystatin is effective as a suspension. Prepare 50 mg/ml stock suspensions in water and store at −20 °C. Stable at 37 °C for 3 days. Use in tissue culture at 50 μg/ml.

Properties

sterility

γ-irradiated

form

powder

packaging

vial of 240,000 units

solubility

H₂O: insoluble

suitability

cell culture tested

storage temp.

−20°C

References

Reference

Brezis, M. Science 224, 66, (1984)

Merck

Merck 13,6770

Safety

Safety Statements

22-24/25

WGK Germany

RTECS

RF5950000

10-8-23

Related Categories

... Antibiotics A to Z > Antibiotics N-S

... Spectrum of Activity > Antifungal

... Mechanism of Action > Interferes with Cell Membrane Permeability (Ionophores)

... Chemical Structure Class > Polyenes

N4014 - General Information (58kb)

N4014 - Product Information Sheet (55kb)

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

More Information