N4279
Sigma

Neuropeptide Y Fragment 3-36 porcine

≥95% (HPLC)

Amino Acid Sequence

Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH₂

Molecular Formula

C₁₇₆H₂₇₁N₅₃O₅₄

Molecular Weight

3993.36

CAS Number

143863-88-1

MDL number

MFCD00241251

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Descriptions

Biochem/physiol Actions

Endogenous neuropeptide that selectively binds to Y₂ and Y₅ receptors.

Properties

assay

≥95% (HPLC)

composition

Peptide content, ~60%

Gene Information

pig ... NPY(397304)

storage temp.

−20°C

References

Reference

Grandt, D., et al., Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul. Pept. 67, 33-37, (1992)

Browning, K.N., and Lees, G.M., Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon. Neurogastroenterol. Motil. 12, 33-41, (2000) abstract

Mentlein, R., et al., Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul. Pept. 49, 133-144, (1993) abstract

Safety

WGK Germany

Related Categories

... Gastrointestinal Peptides > Neuropeptide Y

... Neuropeptide Y and Peptide YY Peptides > Neuropeptide Y

... Obesity Peptides > Y Receptor Ligands

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Certificate of Analysis

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N4279 (Sigma)