N5631
Sigma

Neuraminidase from Clostridium perfringens (C. welchii)

Type VIII, lyophilized powder, 10-20 units/mg protein (using NAN-lactose), ~4 units/mg protein (mucin)

Synonym

Acyl-neuraminyl Hydrolase

Receptor-destroying enzyme

Sialidase

CAS Number

9001-67-6

Enzyme Commission (EC) Number

3.2.1.18 ( BRENDA | IUBMB )

MDL number

MFCD00131711

EG/EC Number

232-624-6

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Descriptions

Biochem/physiol Actions

Hydrolyzes α(2→3), α(2→6), and α(2→8)-glycosidic linkages of terminal sialic residues of various glycomolecules.

Preparation Note

Chromatographically purified from Type V

Unit Definition

One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin unless otherwise specified.

Properties

type

Type VIII

form

lyophilized powder

composition

Protein, ~90% biuret

foreign activity

Protease and NAN-aldolase, present

Gene Information

Clostridium perfringens str. 13 ... nanJ(988807)

storage temp.

−20°C

References

Reference

Cassidy, J.T., et al. J. Biol. Chem. 240, 3501, (1965)

Safety

WGK Germany

RTECS

QQ3450000

10-21