N8648
Sigma

GR 231118

≥95% (HPLC), lyophilized powder

Synonym

1229U91

Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH₂, cyclic (2,4′)(2′,4) diamide

Neuropeptide Y Antagonist

MDL number

MFCD00927773

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Descriptions

Biochem/physiol Actions

High affinity and selective NPY Y₁ receptor antagonist.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Properties

assay

≥95% (HPLC)

form

lyophilized powder

mol wt

calculated mol wt 2353

storage temp.

−20°C

References

Reference

Angus, J.A., new insights into vascular reactivity: from altered structure to neural control. Clin. Exp. Pharmacol. Physiol. 24, 297-304, (1997) abstract

Kennedy, B., et al., Neuropeptide Y-mediated pressor responses following high-frequency stimulation of the rat sympathetic nervous system. J. Pharmacol. Exp. Ther. 281, 291-296, (1997) abstract

Safety

WGK Germany

Related Categories

... Gastrointestinal Peptides > Neuropeptide Y

... Neuropeptide Y and Peptide YY Peptides > Neuropeptide Y

... Neurotransmission (Obesity) > Neuropeptide Y and Peptide YY

MSDS

Certificate of Analysis

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N8648 (Sigma)