Anti-Purinergic Receptor P2Y₁₃ antibody produced in rabbit 

P2Y₁₃ receptor belongs to the G-protein coupled receptors superfamily. Like the P2Y₁₂ receptor it is a high affinity receptor for the ADP nucleotide, coupled to the Ga_i class of G-proteins. The P2Y₁₃ receptor is highly expressed at brain and spleen tissues as well as in the immune system. ADP activates a negative feedback pathway for ATP release from human red blood cells via the P2Y₁₃ receptor. P2Y₁₃ receptor was also implicated in inhibition of N-type Ca²⁺ channels in neurons, exerting pre and/or post-synaptic modulatory action.

peptide DRFLKIIRPLRNIFLK(C) corresponding to residues 119-134 of human P2Y₁₃ receptor.

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

affinity isolated antibody

lyophilized powder

rat

immunoblotting: 1:200 using rat brain membranes

rat ... P2ry13(310444)

dry ice

−20°C

Zhang, F.L., et al. J. Pharmacol. Exp. Ther. 301, 705, (2002) abstract