P1306
Sigma

Peptide YY human

≥97% (HPLC), synthetic

Synonym

PYY

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂

Molecular Formula

C₁₉₄H₂₉₅N₅₅O₅₇

Molecular Weight

4309.75

CAS Number

118997-30-1

MDL number

MFCD00081843

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Descriptions

Biochem/physiol Actions

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Properties

biological source

synthetic

assay

≥97% (HPLC)

Gene Information

human ... PYY(5697)

storage temp.

−20°C

References

Reference

Tatemoto, K., Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion. Proc. Natl. Acad. Sci. USA 79, 2514-2518, (1982)

Lundberg, J.M., Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc. Natl. Acad. Sci. USA 79, 4471-4475, (1982)

Tatemoto, K., Isolation and primary structure of human peptide YY. Biochem. Biophys. Res. Commun. 157, 713-717, (1988)

Safety

WGK Germany