P248
Sigma

Monoclonal Anti-PARP antibody produced in mouse

clone C-2-10, ascites fluid, buffered aqueous solution

Synonym

Monoclonal Anti-Poly[ADP-ribose] Polymerase

MDL number

MFCD01322527

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Descriptions

Immunogen

calf thymus PARP

Specificity

The epitope is found between amino acids 216-375 in the DNA-binding domain of PARP. The antibody reacts with PARP (116 kDa) and the 85 kDa apoptosis-induced cleavage product of prICE (proteinase resembling interleukin 1β-converting enzyme) and caspase-3 (CPP32 cysteine protease).

Physical form

Solution in phosphate buffered saline, containing 7.5 mM sodium azide

Properties

antibody form

ascites fluid

clone

C-2-10

form

buffered aqueous solution

mol wt

antigen mol wt 116 kDa (PARP)

antigen mol wt 85 kDa (prICE/caspase-3 cleavage product)

species reactivity

mouse, rat, hamster, primate

does not react with

avian

application(s)

immunoblotting: 1:2,000

immunocytochemistry: 1:1,000

indirect ELISA: suitable

isotype

IgG1

Gene Information

rat ... Parp1(25591), Parp2_predicted(290027)

mouse ... Parp1(11545), Parp2(11546)

shipped in

dry ice

storage temp.

−20°C

References

Reference

Lamarre, D., et al. Biochim. Biophys. Acta 950, 147, (1988) abstract

Safety

WGK Germany

3

Related Categories

... Antibodies for Apoptosis > Antibodies to PARP

... Clone Index > C

... Alphabetical Index > P1 to PN

P248 - Datasheet (27kb)

P248_ - Datasheet (13kb)

MSDS

Certificate of Analysis

Certificate of Origin

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P248 (Sigma)

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