P2865
Sigma

Prion Protein Fragment 118-135 Human

>90% (HPLC), solid

Amino Acid Sequence

Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly-Gly-Tyr-Met-Leu-Gly-Ser-Ala-Met-Ser

Molecular Formula

C₆₈H₁₁₂N₁₈O₂₂S₂

Molecular Weight

1597.85

CAS Number

202121-03-7

MDL number

MFCD02261954

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Descriptions

Biochem/physiol Actions

Exhibits fusogenic properties through direct interaction with cellular membranes.

Properties

assay

>90% (HPLC)

form

solid

Gene Information

human ... PRNP(5621)

storage temp.

−20°C

References

Reference

Pillot, T., et al., The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion. J. Mol. Biol. 274, 381, (1997)

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... Alzheimers and Neurodegenerative Disease Research > Other

... Neurodegenerative Disease Peptides > Prion Protein Fragments

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Certificate of Analysis

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P2865 (Sigma)