Other Notes
PSA from human seminal fluid; α2-M from human plasma.
Physical form
Solution in 20 mM sodium phosphate, pH 7.4, 150 mM sodium chloride, and 0.05% sodium azide.
Biochem/physiol Actions
Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with chymotrypsin-like enzymatic activity. Circulating PSA exists in free and protease inhibitor-bound forms. Studying the ratios of free to inhibitor-bound forms may prove valuable in the diagnosis of prostate cancer.
Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with chymotrypsin-like enzymatic activity.