P3737
Sigma

Monoclonal Anti-p63 antibody produced in mouse

~2 mg/mL, clone 4A4, purified immunoglobulin, buffered aqueous solution

MDL number

MFCD02263451

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Descriptions

Immunogen

recombinant N-terminal portion (amino acids 1-205) of mouse ΔNp63 isoform.¹

Specificity

By immunoblotting, 3 bands are visible at approx. 50, 60, and 70 kDa using HaCaT cells, and multiple bands of approx. 44, 60, 80, and 90-95 kDa in other preparations.

Legal Information

This product is licensed for RESEARCH USE ONLY under U.S. Patents Nos. 6,946,256 and 7,030,227 owned by Harvard College. Other uses of the Sigma product, for example in diagnostics or therapeutics, are outside the scope of the license and are not authorized. For products licensed for diagnostic use, consult AsymmetRx, Inc. by telephone at 203-228-0209 or by email at pmckeon@asymmetrix.com

Properties

antibody form

purified immunoglobulin

clone

4A4

form

buffered aqueous solution

species reactivity

human, rat, mouse

concentration

~2 mg/mL

application(s)

immunoblotting: 1-2 μg/mL using whole extract of cultured human keratinocyte HaCaT cells

immunocytochemistry: suitable

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

immunohistochemistry (frozen sections): suitable

immunoprecipitation: suitable

indirect ELISA: suitable

microarray: suitable

isotype

IgG2a

Gene Information

mouse ... Trp63(22061)

rat ... Trp63(246334)

human ... TP63(8626)

shipped in

dry ice

storage temp.

−20°C

References

Cited Reference

1. Yang, A., et al., Mol. Cell 2, 305-316, (1998)

Reference

Yang, A., et al. Nature 398, 714-718, (1999) abstract

Liefer, K.M., et al. Cancer Res. 60, 4016-4020, (2000) abstract

Signoretti, S., et al. Am. J. Pathol. 157, 1769-1775, (2000) abstract

Safety

WGK Germany

Related product

P3362, Monoclonal Anti-p63 antibody produced in mouse

Array

CSAA1, Panorama^® Antibody Microarray - Cell Signaling Kit

GRAA2, Panorama^® Antibody Microarray - Gene Regulation I Kit

PPAA4, Panorama^® Antibody Array -p53 pathways

XP725, Panorama^® Antibody Microarray - XPRESS Profiler725 Kit

Related Categories

... Antibodies for Cell Cycle > Antibodies to Nuclear Proteins

... Antibodies for Cell Cycle > Antibodies to p53 and Related Proteins

... Alphabetical Index > P1 to PN

... Clone Index > 4

P3737 - Datasheet (93kb)

MSDS

Certificate of Analysis

More Information