P4547
Sigma

Prostaglandin A₂ solution

10 mg/mL in methyl acetate, ~95%, synthetic

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Synonym

(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid

PGA₂

Molecular Formula

C₂₀H₃₀O₄

Molecular Weight

334.45

CAS Number

13345-50-1

Beilstein Registry Number

2221844

MDL number

MFCD00077859

PubChem Substance ID

24898548

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Descriptions

Biochem/physiol Actions

Blocks cell cycle at G2/M; induces apoptosis in tumor cells; inhibits viral replication; PPARγ agonist.

Properties

biological source

synthetic

assay

~95%

concentration

10 mg/mL in methyl acetate

storage temp.

−20°C

References

Reference

Fukushima. M., et al. Adv. Prostaglandin Thromboxane Leukotriene Res. 19, 415, (1989)

Ohno, K., et al. Chem. Biol. Interact. 78, 67, (1991) abstract

Hayes, M.M., et al., Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects. J. Biol. Chem. 277, 16913, (2002) abstract

Safety

Hazard Codes

F,Xi

Risk Statements

11-36-66-67

Safety Statements

RIDADR

UN 1231 3/PG 2

WGK Germany

Flash Point(F)

16 °F

Flash Point(C)

-9 °C

8-10

Related Categories

... Arachidonic Acid Cascade > Prostaglandins

... Fatty Acids > Prostaglandins

Celltransmissions 20(2) (367kb)

MSDS

Specification Sheet

Certificate of Analysis

More Information

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10 mg/mL in methyl acetate, ~95%, synthetic

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