P5630
Sigma

3,4-Dihydroxybenzoic acid

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Synonym

Protocatechuic acid

Molecular Formula

(HO)₂C₆H₃CO₂H

Molecular Weight

154.12

CAS Number

99-50-3

Beilstein Registry Number

1448841

MDL number

MFCD00002509

EG/EC Number

202-760-0

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Descriptions

Biochem/physiol Actions

Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.

Properties

197-200 °C (dec.)(lit.)

References

Reference

Nakamura, H., et al., Inhibitory effects of protocatechuic acid on the post-initiation phase of hamster pancreatic carcinogenesis induced by N-nitrosobis(2-oxopropyl)amine. Anticancer Res. 20, 3423-3427, (2000)

Tseng, T.H., et al., Induction of apoptosis by hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl-2 expression. Biochem. Pharmacol. 60, 307-315, (2000)

Merck

Merck 13,7986

Beilstein

Beil. 10,IV,1459

reference

Aldrich MSDS 1, 706:D / Corp MSDS 1 (1), 1272:C / FT-IR 2 (2), 2688:C / FT-IR 1 (2), 216:B / FT-NMR 1 (2), 1116:B / IR-Spectra (3), 971:E / IR-Spectra (2), 850:F / NMR-Reference 2 (2), 212:B / RegBook 1 (2), 1805:O / Sax 6, 2319 / Sigma FT-IR 1 (2), 863:D / Structure Index 1, 289:A:2

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

UL0560000