P8014
Sigma

4α-Phorbol 12,13-didecanoate

solid

zoom

1 of 1

Synonym

4α-Phorbol 12-13-dicaprinate

4αPDD

Molecular Formula

C₄₀H₆₄O₈

Molecular Weight

672.93

CAS Number

27536-56-7

Beilstein Registry Number

2514324

MDL number

MFCD00036737

PubChem Substance ID

24898900

Expand/Collapse All

Descriptions

Application

Phorbol that is not biologically active, can be used as a negative control.

Biochem/physiol Actions

Skin tumor promoter in experimental animal model.¹

Caution

Photosensitive

Reconstitution

Stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.

Properties

form

solid

color

white

solubility

DMSO: soluble

ethanol: soluble

methanol: soluble

storage temp.

−20°C

References

Cited Reference

1. Baird, W. M. and Boutwell, R. K., Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin. Cancer Res. 31, 1074-1079, (1971)

Reference

Fukushima, et al. Biochem. J. 320, 27-32, (1996) abstract

LaPointe, et al. Mol. Endocrinol. 7, 1284-1286, (1993)

Rose-Hellekant, et al. Mol. Reprod. Dev. 44, 250-255, (1996) abstract

Safety

Hazard Codes

T+

Risk Statements

26/27/28-40-43

Safety Statements

36/37/39-45

RIDADR

UN 2811 6.1/PG 2

WGK Germany

8-10

Related Categories

... Kinase/Phosphatase Biology > Protein Kinase Activators

... Serine/Threonine Kinase Activators > Protein Kinase C (PKC)

MSDS

Certificate of Analysis

Certificate of Origin

More Information