P9620
Sigma

Puromycin dihydrochloride

Ready Made Solution, from Streptomyces alboniger, 10 mg/mL in H₂O, 0.2 μm filtered

CAS Number

58-58-2

MDL number

MFCD00067313

EG/EC Number

200-387-8

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Descriptions

Biochem/physiol Actions

Puromycin inhibits the growth of a wide range of eukaryotic and prokaryotic cells by interfering with protein synthesis. It allows the selection of cells expressing the pac gene.

Suitability

Tested on HeLa cells for cell growth arrest and selection of cells after transfection of the pac resistance gene.

Properties

biological source

from Streptomyces alboniger

sterility

0.2 μm filtered

assay

>98% (HPLC)

concentration

10 mg/mL in H₂O

suitability

cell culture tested

shipped in

wet ice

storage temp.

−20°C

References

Reference

Tabuchi, I. Biochem. Biophys. Res. Commun. 23, 2-5, (2003)

Eyckerman, S., et al. Nat. Cell Biol. 3, 1114-1116, (2001)

Safety

Risk Statements

Safety Statements

WGK Germany

RTECS

AU7355000

Related Categories

... Essential Biological Reagents > Antibiotics

... Antibiotics A to Z > Antibiotics N-S

... Antibiotics by Application > Antineoplastic and Immunosuppressive Antibiotics

... Spectrum of Activity > Antiparasitic / Antiprotozoal / Anthelminthic

... Antibiotics by Application > Genetic Marker Selection

... Mechanism of Action > Interferes with Protein Synthesis

... Antibacterial > L - Z

... Chemical Structure Class > Peptidyl Nucleosides

... Gene Regulation and Expression > RNA-Protein Translation Inhibitors

P9620 - Datasheet (101kb)

Technical Article Summer 06 (299 K)

MSDS

Certificate of Analysis

Certificate of Origin

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P9620 (Sigma)

Puromycin dihydrochloride

Ready Made Solution, from Streptomyces alboniger, 10 mg/mL in H2O, 0.2 μm filtered

Ready Made Solution, from Streptomyces alboniger, 10 mg/mL in H₂O, 0.2 μm filtered