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Synonym
n
Hexadecanoyl coenzyme A
Molecular Formula
C37H65N7O17P3S · xLi+
Molecular Weight
1004.94 (free acid basis)
CAS Number
MDL number
PubChem Substance ID
Descriptions
Biochem/physiol Actions
Long chain fatty acid (C16) covalently linked to Coenzyme A. Covalent attachment of palmitate is a common occurrence on a wide variety of viral and cellular proteins and plays a role in promoting membrane binding. Palmitoylation may also be a general mechanism for prolonging or potentiating G-protein signaling.
References
Reference
Resh, M. D., et al., Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim. Biophys. Acta 1451, 1, (1999) abstract
Tu, Y., et al., Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits. Science 278, 1132-1135, (1997) abstract
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