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Q110 
Sigma 

Quinelorane dihydrochloride 

crystalline  
  1 of 1  
      
 
Synonym 
(5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
 
 
LY-163,502
 
Molecular Formula
C14H22N4 · 2HCl
 
Molecular Weight
319.27
 
CAS Number 
97548-97-5
MDL number 
MFCD00903730

 
PubChem Substance ID 
24277930

 
 
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Price and Availability
Descriptions
Biochem/physiol Actions  
D2 dopamine receptor agonist; 2-aminopyridine analog of quinpirole.
 
Legal Information  
Manufactured and sold with the permission of Eli Lilly and Company.
 
Properties
form 
crystalline
 
color 
white
 
solubility 
H2O: >10 mg/mL
 
Gene Information 
human ... DRD2(1813)
References
Reference 
Charles, M.A., Effects of LY163,502, a D2 dopaminergic agonist, on the sexual behavior of male rats. Pharmacol. Biochem. Behav. 43, 1087, (1992) abstract
 
 
Eaton, M.J., et al., Effects of the selective dopaminergic D2 agonist quinelorane on the activity of dopaminergic and noradrenergic neurons projecting to the diencephalon of the rat. J. Pharmacol. Exp. Ther. 268, 645, (1994) abstract
 
 
Carlson, J.H. and, Foote, S.L., Oscillation of interspike interval length in Substantia nigra dopmaine neurons: Effects on nicotine and the dopaminergic D2 agonist LY163502 on electrophysiological activity. Synapse 11, 229, (1992) abstract
Safety
WGK Germany 
3
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