Q111
Sigma

(±)-Quinpirole dihydrochloride

solid

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Synonym

trans-(±)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline dihydrochloride

LY-141,865

Molecular Formula

C₁₃H₂₁N₃ · 2HCl

Molecular Weight

292.25

CAS Number

73625-62-4

MDL number

MFCD01321054

PubChem Substance ID

24278670

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Descriptions

Biochem/physiol Actions

D₂-like dopamine receptor agonist that possesses some activity at D₃ sites.

Legal Information

Manufactured and sold with the permission of Eli Lilly and Company.

Properties

form

solid

color

white

solubility

H₂O: 28 mg/mL

Gene Information

human ... DRD2(1813)

storage temp.

−20°C

References

Reference

Munro, L.J., Kokkinidis, L., Infusion of quinpirole and muscimol into the ventral tegmental area inhibits fear-potentiated startle: Implications for the role of dopamine in fear expression. Brain Res. 746, 231-238, (1997) abstract

Kebabian, et al., Compounds selective for dopamine receptor subtypes. Drug Discov. Today 2, 333-340, (1997)

Eilam, D., Szechtman, H., Biphasic effect of D₂ agonist quinpirole on locomotion and movements. Eur. J. Pharmacol. 161, 151-157, (1989) abstract

Rosenzweig-Lipson, S., Barrett, J.E, K-Channel blockers attenuate the presynaptic effects of the D₂/D₃ agonist quinpirole in monkeys. Pharmacol. Biochem. Behav. 51, 843-848, (1995) abstract

Safety

WGK Germany

RTECS

UR0809270

Related Categories

... Dopaminergics > Agonists

MSDS

Certificate of Analysis

More Information

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Q111 (Sigma)