R0529
Sigma

Ro 90-7501

≥98% (HPLC)

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Synonym

2′-(4-Aminophenyl)-[2,5′-bi-1H-benzimidazol]-5-amine

Molecular Formula

C₂₀H₁₆N₆

Molecular Weight

340.38

CAS Number

293762-45-5

MDL number

MFCD07784512

PubChem Substance ID

24724587

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Descriptions

Biochem/physiol Actions

Inhibitor of Aß₄₂ fibril formation

Properties

assay

≥98% (HPLC)

form

solid

color

brown

solubility

DMSO: ~20 mg/mL

H₂O: insoluble

References

Reference

Bohrmann, B., et al., Self-assembly of β-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J. Struct. Biol. 130, 232-246, (2000) abstract

Ross, C.A., and Poirier, M.A., Protein aggregation and neurodegenerative disease. Nat. Med. 10 Suppl., S10-S17, (2004) abstract

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36/37

WGK Germany

Related Categories

... Alzheimers and Neurodegenerative Disease Research > Other

MSDS

Certificate of Analysis

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R0529 (Sigma)