RNAlater^® 

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• Rapidly permeates tissues to stabilize and protect cellular RNA with immediate RNase inactivation
• Stabilizes samples at room temperature for up to one week or indefinitely at -20 °C for archiving needs
• No compromise in RNA quality following mRNA or total RNA isolation
• Aqueous non-toxic solution allows downstream tissue processing

RNAlater^® is an aqueous, non-toxic tissue and cell storage reagent that stabilizes and protects cellular RNA in intact, unfrozen tissue and cell samples. RNAlater eliminates the need to immediately process samples or to freeze samples in liquid nitrogen for later processing. RNAlater can be used with various downstream applications including mRNA and total RNA isolation, histology and immunocytochemistry and is compatible with Sigma's GenElute^™ isolation kits.

RNAlater is easy to use. Simply cut tissue samples to be stored so they are less than 0.5 cm in at least one dimension and submerge in 5 volumes of RNAlater. Small organs, such as rat kidney, liver or spleen can be stored in whole in RNAlater. When ready to isolate the RNA, remove the tissue from RNAlater and process as though just harvested. For cell storage, resuspend pelleted cells in a small amount of PBS before adding 5-10 volumes of RNAlater. Before preparing RNA, pellet cells and discard supernatant.

Licensed for distribution by Ambion, Inc., The RNA Company.
RNAlater is a registered trademark of Ambion, Inc., Austin, Texas and is protected by various U.S. and foreign patents.

RNAlater is a registered trademark of Ambion, Inc.

GenElute is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.

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