R134
Sigma

Rilmenidine hemifumarate salt

solid

Synonym

Oxaminozoline hemifumarate salt

Rilmenidene hemifumarate salt

N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine hemifumarate salt

Molecular Formula

C₁₀H₁₆N₂O � 0.5C₄H₄O₄

Molecular Weight

238.28

CAS Number

207572-68-7

MDL number

MFCD00673925

PubChem Substance ID

24277752

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Descriptions

Biochem/physiol Actions

Selective I₁ imidazoline receptor agonist.

Properties

form

solid

color

white

solubility

DMSO: >10 mg/mL

H₂O: insoluble

Gene Information

human ... NISCH(11188)

References

Reference

Chan, C.K., et al., Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits. J. Pharmacol. Exp. Ther. 276, 411, (1998)

Takada, K., et al., The involvement of pertussis toxin-sensitive G proteins in the post receptor mechanism of central I₁-imidazoline receptors. Br. J. Pharmacol. 120, 1575, (1997) abstract

Ozog, M., et al., Rilmenidine elevates cytosolic free calcium concentration in suspended cerebral astrocytes. J. Neurochem. 71, 1429-1435, (1998) abstract

Safety

Safety Statements

22-24/25

WGK Germany

RTECS

RP7207400