R6400
Sigma

Anti-phospho-Retinoblastoma (pSer^807,811) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym

Anti-phospho-Rb (pSer^807,811)

MDL number

MFCD02097167

Expand/Collapse All

Descriptions

Immunogen

synthetic peptide corresponding to residues around phosphoserine 807/811 of the human retinoblastoma tumor suppressor protein (Rb), conjugated to KLH.

Preparation Note

Purified using protein A and peptide affinity chromatography.

Specificity

Recognizes phosphorylated Rb (Ser⁸⁰⁷/Ser⁸¹¹) and does not react with non-phosphorylated Rb. Does not react with Rb phosphorylated at other sites.

Physical form

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol.

Properties

antibody form

affinity isolated antibody

form

buffered aqueous glycerol solution

species reactivity

human, rat, mouse

application(s)

immunoblotting (chemiluminescent): 1:1,000 using human fibroblasts synchronized by serum deprivation

Gene Information

mouse ... Rb1(19645)

human ... RB1(5925)

rat ... Rb1(24708)

shipped in

wet ice

storage temp.

−20°C

Safety

WGK Germany

Related Categories

... Antibodies for Cell Cycle > Antibodies to Nuclear Proteins

... Antibodies for Cell Cycle > Antibodies to Retinoblastoma (Rb) and Related Proteins

... Alphabetical Index > R

... Tumor Growth Regulation > Tumor Suppressor Gene Products

R6400 - Datasheet (27kb)

MSDS

Certificate of Analysis

More Information

Anti-phospho-Retinoblastoma (pSer807,811) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Anti-phospho-Retinoblastoma (pSer^807,811) antibody produced in rabbit