S1437
Sigma

Sex Hormone-Binding Globulin from human serum

≥95% (SDS-PAGE), buffered aqueous glycerol solution

Synonym

SHBG

Testosterone-estradiol binding globulin

MDL number

MFCD00163748

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Descriptions

Biochem/physiol Actions

Dimeric plasma glycoprotein with high affinity for the gonadal steroids, testosterone, and estradiol. Regulates the availability of sex steroid hormones and limits their access to target cells. Inhibits estradiol-induced proliferation of breast cancer cells.

Physical form

Solution in 20 mM Tris-HCl, 10% Glycerol, pH 7.4

Properties

assay

≥95% (SDS-PAGE)

form

buffered aqueous glycerol solution

Gene Information

human ... SHBG(6462)

shipped in

dry ice

storage temp.