S168
Sigma

N-Allyl-(±)-SKF-38393 hydrobromide

solid, ≥98% (HPLC)

zoom

1 of 1

Synonym

(±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

(±)-SKF-77434 hydrobromide

Molecular Formula

C₁₉H₂₁NO₂ · HBr

Molecular Weight

376.29

CAS Number

300561-58-4

MDL number

MFCD00243077

PubChem Substance ID

24277936

Expand/Collapse All

Descriptions

Biochem/physiol Actions

Centrally active D₁ dopamine receptor agonist.

Caution

Light sensitive

Properties

assay

≥98% (HPLC)

form

solid

storage condition

protect from light

color

white or off-white

solubility

ethanol: 3.2 mg/mL

DMSO: >50 mg/mL

H₂O: 6.0 mg/mL

0.1 M HCl: 6.3 mg/mL

Gene Information

human ... DRD1(1812)

storage temp.

2-8°C

References

Reference

Tidey, J.W, et al., Drug discrimination in methamphetamine-trained monkeys: Agonist and antagonist effects of dopaminergic drugs. J. Pharmacol. Exp. Ther. 285, 1163-1174, (1998) abstract

Smith, S.E. et al., Evidence that the enhancement of dopamine function by repeated electroconvulsive shock requires concomitant activation of D₁-like and D₂-like dopamine receptors. Psychopharmacology Berl. 133, 77, (1997) abstract

Weed, M.R, et al., The relationship between reinforcing effects and in vitro effects of D₁ agonists in monkeys. J. Pharmacol. Exp. Ther. 283, 29-38, (1997) abstract

Safety

WGK Germany

Related Categories

... Dopaminergics > Agonists

MSDS

Certificate of Analysis

More Information

Related Categories

Printer Friendly View

Ask A Scientist

Email Page

Last 5 Products Viewed

S168 (Sigma)