S178
Sigma

(R)-SKF-82957 hydrobromide

solid

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Synonym

(1R) - 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1-phenyl-1H-3-benzazepine-7,8-diol hydrobromide

Molecular Formula

C₁₇H₁₈ClNO₂ · HBr

Molecular Weight

384.70

CAS Number

288262-87-3

PubChem Substance ID

24899494

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Descriptions

Biochem/physiol Actions

Selective D₁ dopamine receptor agonist.

Caution

hygroscopic, photosensitive

Properties

form

solid

optical activity

[α]22/D +22.46°, c = 0.76 in DMF(lit.)

color

white

solubility

H₂O: 7.5 mg/mL

DMSO: soluble

References

Reference

Andersen, P.H. and, Jansen, J.A., Dopamine receptor agonists: Selectivity and dopamine D1 receptor efficacy. Eur. J. Pharmacol. 188, 335, (1990) abstract

Pfeiffer, et al., Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines. J. Med. Chem. 25, 352, (1982) abstract

Safety

WGK Germany

Related Categories

... Dopaminergics > Agonists

MSDS

Certificate of Analysis

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