S3672
Sigma

[Sar⁹, Met(O₂)¹¹]-Substance P

≥97% (HPLC)

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Synonym

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O₂]-NH₂

Molecular Formula

C₆₄H₁₀₀N₁₈O₁₅S

Molecular Weight

1393.66

CAS Number

110880-55-2

MDL number

MFCD00076787

PubChem Substance ID

24899567

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Descriptions

Biochem/physiol Actions

Highly selective NK-1 receptor agonist.

Properties

assay

≥97% (HPLC)

storage temp.

−20°C

References

Reference

Hood, V.C., et al., Differential role of neurokinin receptors in human lymphocyte and monocyte chemotaxis. Regul. Pept. 96, 17-21, (2000) abstract

Jenkinson, K.M., et al., Independent endocytosis of the NK-1 and NK-3 tachykinin receptors in neurons of the rat myenteric plexus. Neuroscience 100, 191-199, (2000) abstract

Yip, J., et al., Distribution of Fos-like immunoreactivity in guinea-pig brain following administration of the neurokinin-1 receptor agonist[SAR⁹MET(O2)¹¹]substance. P. Neuroscience 94, 663-673, (1999)

Safety

WGK Germany

Related Categories

... Tachykinins > Agonist

... Neuropeptides > Tachykinins

... Neurotransmission (Obesity) > Tachykinins

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

More Information

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≥97% (HPLC)

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