S6636
Sigma

[Sar⁹]-Substance P

≥97% (HPLC)

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Synonym

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met-NH₂

Molecular Formula

C₆₄H₁₀₀N₁₈O₁₃S

Molecular Weight

1361.66

CAS Number

77128-75-7

MDL number

MFCD00080118

PubChem Substance ID

24899717

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Descriptions

Biochem/physiol Actions

NK-1 receptor agonist.

Properties

assay

≥97% (HPLC)

storage temp.

−20°C

References

Reference

Hill, C.E., and Gould, D.J., Modulation of sympathetic vasoconstriction by sensory nerves and nitric oxide in rat irideal arterioles. J. Pharmacol. Exp. Ther. 273, 918-926, (1995) abstract

Perretti, M., et al., Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors. Immunology 80, 73-77, (1993) abstract

Safety

WGK Germany