Streptomycin sulfate salt 

Recommended for use in cell culture applications at 100 mg/L. Stock solutions should be sterile-filtered and stored at 2-8 °C for up to a month or at −20 °C for extended periods. Solutions are stable at 37 °C for 3 days.

Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation.
Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

powder

≥720 I.U. per mg

cell culture tested

2-8°C

Merck 13,8905

Beil. 18,V,11,82

Xn

22

WK4990000

3