T3146
Sigma

Trimipramine maleate salt

≥98% (TLC), powder

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Molecular Formula

C₂₀H₂₆N₂ � C₄H₄O₄

Molecular Weight

410.51

CAS Number

521-78-8

MDL number

MFCD00082376

PubChem Substance ID

24278731

EG/EC Number

208-318-3

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Descriptions

Biochem/physiol Actions

Antidepressant; serotonin transport blocker that also blocks norepinephrine uptake.

Properties

assay

≥98% (TLC)

form

powder

color

white

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

storage temp.

2-8°C

References

Reference

Chouinard, et al., Metabolism of anxiolytics and hypnotics: benzodiazepines, buspirone, zopiclone, and zolpidem. Cell. Mol. Neurobiol. 19, 533-552, (1999) abstract

Plenge-Tellechea, et al., Tricyclic antidepressants inhibit the Ca²⁺-dependent ATPase activity from plasma membrane. Arch. Biochem. Biophys. 370, 119-125, (1999) abstract

Langosch, et al., Effects of the atypical antidepressant trimipramine on field potentials in the low Mg²⁺-model in guinea pig hippocampal slices. Eur. Neuropsychopharmacol. 8, 209, (1998) abstract

Safety

Hazard Codes

Risk Statements

22-36/37/38-63

Safety Statements

26-36

WGK Germany

RTECS

HN9260000