T3410
Sigma

Thymosin�α₁ bovine

≥90% (HPLC)

Synonym

Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

Molecular Formula

C₁₂₉H₂₁₅N₃₃O₅₅

Molecular Weight

3108.28

CAS Number

62304-98-7

MDL number

MFCD00076889

Expand/Collapse All

Descriptions

Biochem/physiol Actions

Hormone produced by thymic stromal cells that can augment host defense mechanisms, by increasing the production of T cells by thymus and restoring T cell-mediated antibody production in immunodeficient animals..

Properties

assay

≥90% (HPLC)

storage temp.

−20°C

References

Reference

Ohmori, H., et al., Restoration of immunocyte functions by thymosin alpha1 in cyclophosphamide-induced immunodeficient mice. Immunopharmacol. Immunotoxicol. 23, 75-82, (2001)

Roy, R., et al., Mechanism of thymocyte apoptosis induced by serum of tumor-bearing host: the molecular events involved and their inhibition by thymosin α-1. Int. J. Immunopharmacol. 22, 309-321, (2000)

Turrini, P., and Aloe, L., Evidence that endogenous thymosin alpha-1 is present in the rat central nervous system. Neurochem. Int. 35, 463-470, (1999)

Safety

WGK Germany

Related Categories

... Immunomodulators > Immunomodulators

MSDS

Specification Sheet

Certificate of Analysis

More Information

Thymosin�α1 bovine

≥90% (HPLC)

Thymosin�α₁ bovine