T3660
Sigma

Calcitonin salmon

≥97% (HPLC), powder

1 of 1

Synonym

Thyrocalcitonin

Amino Acid Sequence

Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂ [Disulfide bridge: 1-7]

Molecular Formula

C₁₄₅H₂₄₀N₄₄O₄₈S₂

Molecular Weight

3431.85

CAS Number

47931-85-1

MDL number

MFCD00133859

PubChem Substance ID

24900157

EG/EC Number

256-342-8

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Descriptions

Biochem/physiol Actions

Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.

Other Notes

32 amino acid polypeptide, 8 of which are conserved across all species.

Properties

assay

≥97% (HPLC)

form

powder

storage temp.

−20°C

References

Reference

Tenenhouse, A., et al. Proc. Natl. Acad. Sci. USA 53, 818, (1965)

Brewer, H.B., et al. J. Biol. Chem. 2454, 4232, (1970)

Farley, J. R., et al. Endocrinology 123, 159, (1988)

Schlueter, et al. Endocrinology 81, 854, (1967)

Merck

Merck 13,1642

Safety

Safety Statements

22-24/25

WGK Germany

RTECS

EV8000000

3-10

Related Categories

... Other Protein/Peptide Hormones > Calcitonin

... Cytokines Growth Factors and Hormones (Obesity) > Calcitonin and Related Products

... Thyroid Hormones > Calcitonins

MSDS

Certificate of Analysis

Certificate of Origin

More Information