T5050
Sigma

Transforming Growth Factor-β1 from porcine platelets

powder, cell culture tested

Synonym

TGF-β1

MDL number

MFCD00166089

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Descriptions

Analysis Note

The biological activity is measured by its ability to inhibit the IL-4-dependent proliferation of mouse HT-2 cells.

Biochem/physiol Actions

TGF-β1 is produced by many cell types, but is reported to be most concentrated in mammalian platelets, where it is present at approximately four times the level of TGF-β2.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.05 mg bovine serum albumin.

Properties

assay

≥97% (SDS-PAGE and N-terminal analysis)

form

powder

potency

0.01-0.1 ng/mL ED₅₀/EC₅₀

mol wt

protein mol wt 25 kDa

total impurities

Endotoxin, tested

suitability

cell culture tested

storage temp.

−20°C

References

Reference

Roberts, A., Sporn, M., The transforming growth factors. Peptide Growth Factors and their Receptors I New York, NY , (1991), 419

Related Categories

... Hematopoietic Stem Cell Expansion/Differentiation > Cytokine/Growth Factor

... Cytokines/Growth Factors/Chemokines > Growth Factors

... Transforming Growth Factor-β (TGF-β) and Superfamily > TGF-β

... Cytokines & Growth Factors > Transforming Growth Factor-b Superfamily Proteins and Peptides

... Growth Factors and Cytokines > Transforming Growth Factors

T5050 - Datasheet (24kb)

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

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T5050 (Sigma)