TOX2
Sigma

In Vitro Toxicology Assay Kit, XTT based

Descriptions

Application

For spectrophotometric measurement of cell viability by mitochodrial dehydrogenase. Absorbance of converted dye is measured at a wavelength of 450 nm.

Biochem/physiol Actions

Conversion of XTT to a water-soluble colored formazan derivative.

Properties

usage

1 kit sufficient for 1,000 tests

storage temp.

−20°C

References

Reference

Roehm, N., et al., An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J. Immunol. Methods 142, 257-265, (1991) abstract

Scudiero, D., et al., Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other cell lines. Cancer Res. 48, 4827-4833, (1988) abstract

Weislow, O., et al., New soluble-formazan assay for HIV-1 cytopathic effects: Application to high-flux screening of synthetic and natural products for AIDS-antiviral activity. J. Natl. Cancer Inst. 81, 577-586, (1989) abstract

Safety

Safety Statements

22-24/25

WGK Germany