V3003
Sigma

Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse

clone 260.4, KDR-2, ascites fluid

Synonym

Anti-KDR

Anti-VEGFR-2

Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse

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Descriptions

Antigen Background

The KDR receptor (VEGFRa), defining marker of hematopoietic stem cells (HSCs), distinguishes pluripotent HSCs from lineage-committed progenitor HSCs.

Immunogen

purified recombinant human extracellular VEGF receptor-2 (KDR).

Specificity

Reacts specifically with human VEGF receptor-2. This clone has also been termed 260.4. It does not recognize Flt1 (VEGFR-1), Flt4 (VEGFR-3), or platelet-derived growth factor receptor (PDGF-R).

Properties

antibody form

ascites fluid

clone

260.4, KDR-2

contains

15 mM sodium azide

species reactivity

human

application(s)

immunoblotting: 1:500 using insect cell culture supernatant expressing human extracellular recombinant VEGFR

immunohistochemistry (frozen sections): suitable

indirect ELISA: suitable

isotype

IgG1

Gene Information

human ... KDR(3791)

shipped in

dry ice

storage temp.

−20°C

References

Reference

Ziegler, B.L., A key marker defining hematopoietic stem cells. Science 285, 1553, (1999)

Safety

WGK Germany

Related Categories

... Angiogenesis > Antibodies to Angiogenic Factors

... Hematopoietic Stem Cell Characterization/Differentiation > Antibodies to Growth Factor Receptors

... Antibodies to Cytokines and Growth Factors > Antibodies to Vascular Endothelial Growth Factor (VEGF)

... Cytokines & Growth Factors > Antibodies to Vascular Endothelial Growth Factor and Receptors

... Clone Index > K

... Alphabetical Index > V

... Receptor Tyrosine Kinase Antibodies > Vascular Endothelial Growth Factor Receptor (VEGFR)

... Vascular Endothelial Growth Factor (VEGF) > VEGF Receptors

V3003 - Datasheet (29kb)

MSDS

Certificate of Analysis

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