Vasoactive Intestinal Peptide human, porcine, rat 

Neuropeptide that is widely distributed in the central and peripheral nervous systems. It is a vasodilator, bronchodilator and smooth muscle relaxant. It modulates the activity of many immune system cell types. It is a mitogen for embryonic sympathetic neurons. Its neuroprotective actions are mediated by the release of activity-dependent neurotrophic factors from glial cells.

≥95% (HPLC)

powder

human ... VIP(7432)

−20°C

Gozes, I., and Brenneman, D.E.,, A new concept in the pharmacology of neuroprotection. J. Mol. Neurosci. 14, 61-68, (2000)

Lu, N., et al., A paradigm for distinguishing the roles of mitogenesis and trophism in neuronal precursor proliferation. Brain Res. Brain Res. Rev. 94, 31-36, (1996)

Goetzl, E.J., et al., Selectivity of effects of vasoactive intestinal peptide on macrophages and lymphocytes in compartmental immune responses. Ann. N.Y. Acad. Sci. 840, 540-550, (1998)

Henning, R.J., and Sawmiller, D.R., Vasoactive intestinal peptide: cardiovascular effects. Cardiovasc. Res. 49, 27-37, (2001)

Bodanszky, M., et al. Proc. Natl. Acad. Sci. USA 70, 382, (1973)

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