| Z340677 Sigma |
Apoptosis: A Practical Approach |
General description
This text provides conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis as distinguished from necrosis and nonspecific cell DNA damage are followed by a systematic examination of the established and the principal noval methodologies utilized in apoptosis research.
Table of Contents
1. Overview of apoptosis, George P. Studzinski
2. Morphological recognition of apoptotic cells,
3. Assessment of DNA damage in apoptosis,
4. Analysis of cell death by flow and laser-scanning cytometry,
5. Cell-mediated cytotoxicity and cell death receptors,
6. Sphingolipids as messengers of cell death,
7. Cytochemical detection of cytoskeletal and nucleoskeletal changes during apoptosis,
8. Metabolic alterations associated with apoptosis,
9. Methods of measuring Bcl-2 family proteins and their functions,
10. Methods for detecting proteolysis during apoptosis in intact cells,
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Index
2. Morphological recognition of apoptotic cells,
3. Assessment of DNA damage in apoptosis,
4. Analysis of cell death by flow and laser-scanning cytometry,
5. Cell-mediated cytotoxicity and cell death receptors,
6. Sphingolipids as messengers of cell death,
7. Cytochemical detection of cytoskeletal and nucleoskeletal changes during apoptosis,
8. Metabolic alterations associated with apoptosis,
9. Methods of measuring Bcl-2 family proteins and their functions,
10. Methods for detecting proteolysis during apoptosis in intact cells,
List of Suppliers
Index
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