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General description
This is the first book to cover the cell cycle field in the wake of groundbreaking research from the past five years. A historical look at cell cycle findings places this new knowledge into perspective and demonstrates the universality of cell cycle control, from the evolutionary process to cancer research and mitotic regulation.
Table of Contents
1. Introduction to cell cycle controls
2. A brief history of the cell cycle 3. START and the G1-S phase transition in budding yeast 4. Controlling entry into mitosis in fission yeast 5. The cdc2 kinase: structure, activation and its role at mitosis in vertebrate cells 6. Cyclin-dependent kinases: an embarrassment of riches 7. S Phase and its regulation 8. Cell cycle progression and cell growth in mammalian cells: kinetic aspects of transition events 9. Cancer and the cell cycle 10. Regulation of the cell cycle during Drosophila development
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