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General description
This book bridges the rapidly growing fields of cellular aging and programmed cell death. It presents an authoritative overview of both fields, and demonstrates how both fields are critical to understanding the aging process. The role of apoptosis in a variety of age-associated diseases and disabilities is also covered.
Table of Contents
Partial table of contents:
BASIC MECHANISMS OF AGING. Genetics of Aging and Longevity in Lower Organisms (T. Johnson, et al.). Mitochondrial DNA Mutations and Aging (E. Schon, et al.). Protein Damage and Oxidative Stress (T. Tabatabaie & R. Floyd). MOLECULAR MECHANISMS CONTROLLING CELLULAR SENESCENCE. Molecular Genetics of In Vitro Cellular Senescence (C. Afshari & J. Barrett). Mechanisms of Escaping Senescence in Human Diploid Cells (W. Wright & J. Shay). PROGRAMMED CELL DEATH: MECHANISMS AND ROLE IN DEVELOPMENT, AGING AND DISEASE. The Biology of Cell Death and Its Relationship to Aging (R. Lockshin & Z. Zakeri). Programmed Cell Death During Development of Animals (C. Milligan & L. Schwartz). Neuronal Loss in Aging and Disease (B. Wolozin, et al.). Index.
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