General description
An international panel of contributors combine to create this exhaustive treatise. General topics include origins of replication, priming, role of transcription factors in replication, fidelity and repair, chromatin structure, and comparisons to prokaryotic mechanisms. A section on proteins includes chapters on cellular and viral DNA polymerases, accessory proteins, ligases, topoisomerases, and telomerases. Finally, about half the book is devoted to discussion of specific replication systems including eleven viruses, yeast, insects, plants, mammals, organelles, and more.