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Z379689 
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Endothelin: Molecular Biology, Physiology, and Pathology 

 
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General description  
Academic, clinical, and pharmaceutical researchers summarize the dramatic recent progress in endothelin research and speculate on future studies. The respected contributors critically evaluate and synthesize our knowledge of endothelin chemistry, its mechanism of action, and its physiological function. Biochemists studying the role of endothelin in cardiovascular physiology and medicinal chemists developing endothelin-centric drugs will find the book rich in insights.

 
 
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ISBN-10 
0-89603-436-4

 
ISBN-13 
978-0-89603-436-5
 
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publication info 
R.F. Highsmith, ed., Humana Press, 1998, 274 pp., hard cover
Table of Contents
Endothelin Receptor Subtypes and Tissue Distribution. Molecular Biology of the Endothelin Receptors. Molecular Biology of Endothelin-Converting Enzyme (ECE). Endothelin Receptor-Signaling Mechanisms in Vascular Smooth Muscle. Mechanisms of Endothelin-Induced Mitogenesis in Vascular Smooth Muscle, The Renal and Systemic Hemodynamic Actions of Endothelin. The Development of Specific Endothelin-Receptor Antagonists, Pathophysiological Role of Endothelin and Potential Therapeutic Targets for Receptor Antagonists. Index.
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